CD4 / Tri-Color / S3.5

Product Details
Description CD4 Monoclonal Antibody (S3.5), TRI-COLORâ„¢
Conjugate Tri-Color
Clone S3.5
Target Species Human
Applications FC
Supplier Thermo Fisher Scientific
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About CD4
This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]
About Tri-Color
Tri-Color is identical to the PE-Cy5/ PE-Cyanine 5 tandem fluorophore for use in flow cytometry.
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