CD14 / Qdot 800 / TUK4
Product Details
Description | CD14 Monoclonal Antibody (TuK4), Qdot™ 800 | |
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Conjugate | Qdot 800 | |
Clone | TUK4 | |
Target Species | Human | |
Applications | FC | |
Supplier | Thermo Fisher Scientific | |
Catalog # | Sign in to view product details, citations, and spectra | |
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About CD14
The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide, and to viruses. This gene has been identified as a target candidate in the treatment of SARS-CoV-2-infected patients to potentially lessen or inhibit a severe inflammatory response. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2020]
The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide, and to viruses. This gene has been identified as a target candidate in the treatment of SARS-CoV-2-infected patients to potentially lessen or inhibit a severe inflammatory response. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2020]
About Qdot 800
Qdot® 800 from Thermo Fisher Scientific is an inorganic nanocrystal with a surface functionalized to allow antibodies and biomolecules to be cross-linked. It is most efficiently excited between 320-405 nm but is capable of excitation across every laser less than its emission peak. It is significantly brighter and more photostable than traditional organic fluorophores, making it still useful for fluorescence microscopy, however its size and solubility issues make it a challenge to use in flow cytometry. In spectral flow cytometry it may still prove useful due to its very unique spectral characteristics
Qdot® 800 from Thermo Fisher Scientific is an inorganic nanocrystal with a surface functionalized to allow antibodies and biomolecules to be cross-linked. It is most efficiently excited between 320-405 nm but is capable of excitation across every laser less than its emission peak. It is significantly brighter and more photostable than traditional organic fluorophores, making it still useful for fluorescence microscopy, however its size and solubility issues make it a challenge to use in flow cytometry. In spectral flow cytometry it may still prove useful due to its very unique spectral characteristics
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Validation References
PMID 21211588 | |
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PMID 22554464 | |
PMID 24999737 | |
PMID 25919308 | |
Additional Sources |
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