CD8a / PE-Texas Red / 5H10

Product Details
Description CD8 alpha Monoclonal Antibody (5H10), PE-Texas Red
Conjugate PE-Texas Red
Clone 5H10
Target Species Mouse
Applications FC
Supplier Thermo Fisher Scientific
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About CD8a
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020]
About PE-Texas Red
PE-Texas Red is a red-emitting tandem fluorophore that combines pycoerythrin (PE) and Texas Ted. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Texas Red. PE-Texas Ted has an excitation peak at 565 nm and an emission peak at 615 nm. It is spectrally comparable to PE-eFluor™ 610, PE-Dazzle 594 and PE-CF®594.
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