CD86 / PE-Alexa 700 / BU63

Product Details
Description CD86 Monoclonal Antibody (BU63), PE-Alexa Fluor 700
Conjugate PE-Alexa 700
Clone BU63
Target Species Human
Applications FC
Supplier Thermo Fisher Scientific
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About CD86
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]
About PE-Alexa 700
PE-Alexa 700 from Thermo Fisher Scientific has an excitation peak at 565 nm and an emission peak at 719 nm. It is useful for flow cytometry applications. PE-Alexa 700 is an alternative to PE-Cy5.5.
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