MHC I beta 2 Microglobulin / DyLight 650 / BBM.1

Product Details
Description Binds human beta 2-Microglobulin, a component of MHC class I molecules, which are present on all nucleated cells (excludes red blood cells) and involved in the presentation of peptide antigens to the immune system.
Conjugate DyLight 650
Clone BBM.1
Target Species Human
Applications ICC, IF, WB, IHC
Supplier Novus Biologicals
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About MHC I beta 2 Microglobulin
This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.[provided by RefSeq, Aug 2014]
About DyLight 650
DyLight™ 650 is a red-emitting fluorophore that excited by the 640 nm laser and collected using a 670/30 nm bandpass filter. DyLight™ 650 has an excitation peak at 652 nm and an emission peak at 672 nm, and is spectrally similar to Alexa Fluor™ 647 and Cy5. DyLight™ 650 is most commonly used in flow cytometery and fluorescence microscopy applications.
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