CLEC6a / Unconjugated / 545925
Product Details
| Description | Human Dectin-2/CLEC6A Antibody | |
|---|---|---|
| Conjugate | Unconjugated | |
| Clone | 545925 | |
| Target Species | Human | |
| Applications | FC, CyTOF | |
| Supplier | R&D Systems | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About CLEC6a
The protein encoded by this gene is a type II membrane receptor with an extracellular C-type lectin-like domain fold. The extracellular portion binds structures with a high mannose content and has been shown to recognize several pathogens, including C. elegans, S. cerevisiae, M. tuberculosis, C. neoformans, and house dust mite. When stimulated, the encoded protein initiates signalling through the CARD9-Bcl10-Malt1 pathway, leading to the induction of cytokines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
The protein encoded by this gene is a type II membrane receptor with an extracellular C-type lectin-like domain fold. The extracellular portion binds structures with a high mannose content and has been shown to recognize several pathogens, including C. elegans, S. cerevisiae, M. tuberculosis, C. neoformans, and house dust mite. When stimulated, the encoded protein initiates signalling through the CARD9-Bcl10-Malt1 pathway, leading to the induction of cytokines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
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236 CLEC6a antibodies from over 15 suppliers available with over 41 conjugates.
