CCR7 / Spark NIR 685 / G043H7
Product Details
Description | Spark NIR 685 anti-human CD197 (CCR7) | |
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Conjugate | Spark NIR 685 | |
Clone | G043H7 | |
Target Species | African Green Monkey, Baboon, Cynomolgus, Human, Rhesus | |
Applications | FC | |
Supplier | BioLegend | |
Catalog # | Sign in to view product details, citations, and spectra | |
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About CCR7
The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
About Spark NIR 685
Spark NIR® 685 from Biolegend is a fluorophore designed for spectral flow cytometry with an excitation peak at 633 nm and an emission peak at 685 nm. This fluorophore is an alternative to Alexa Fluor™ 660 and can be efficiently excited by the 633 nm laser and can be unmixed from Alexa Fluor™ 647 and Alexa Fluor™ 700.
Spark NIR® 685 from Biolegend is a fluorophore designed for spectral flow cytometry with an excitation peak at 633 nm and an emission peak at 685 nm. This fluorophore is an alternative to Alexa Fluor™ 660 and can be efficiently excited by the 633 nm laser and can be unmixed from Alexa Fluor™ 647 and Alexa Fluor™ 700.
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