PI3K p85 alpha / PE / REAL589

Product Details

Description	Clone REAL589 is an antibody fragment derived from the full PI3K p85 alpha antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. \| Clone REAL589 recognizes the human Phosphoinositide 3-kinase (PI3K), also known as phosphatidylinositol 3-kinase which belongs to the family of related intracellular signal transducer enzymes. PI3Ks are involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. Mutations in the gene promote the development of diseases such as allergies, heart diseases, inflammatory processes or cancer. The superfamily of PI3 Kinases consists of several enzymes, which are structurally closely related. \| For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).
Conjugate	PE
Clone	REAL589
Target Species	Human
Applications	MICS (MACSima Imaging Cyclic Staining), IF, IHC
Supplier	Miltenyi Biotec
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About PE
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.

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