Actin gamma / PE / REAL571

Product Details

Description	Clone REAL571 is an antibody fragment derived from the full beta-Actin antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. \| Clone REAL571 recognizes beta-Actin, which belongs to the actin family of highly conserved globular multi-functional proteins that play a role in various types of cell motility. They are able to form microfilaments and are found in all eukaryotic cells. beta-Actin is a nonmuscle cytoskeletal actin and exists in most cell types as a component of the cytoskeleton and as a mediator of internal cell motility. Mutatations in this gene may be associated with diffuse large B- cell lymphoma. \| For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). \|
Conjugate	PE
Clone	REAL571
Target Species	Human
Applications	MICS (MACSima Imaging Cyclic Staining), IF, IHC
Supplier	Miltenyi Biotec
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About PE
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.

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