Vesicular Glutamate Transporter 1 / APC / REA1166

Product Details
Description Clone REA1166 recognizes the mouse and rat VGLUT1, a vesicular glutamate transporter, also known as Slc17a7 or Bnpi. Glutamate transporters belong to a family of neurotransmitter transporter proteins which consists of two classes, EAAT (excitatory amino acid transportesr) and VGLUT (vesicular glutamate transporters). VGLUTs are located in the membrane of glutamate-containing synaptic vesicles and regulate the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. | Additional information: Clone REA1166 displays negligible binding to Fc receptors.
Conjugate APC
Clone REA1166
Target Species Mouse, Rat
Applications MICS (MACSima Imaging Cyclic Staining), IF, IHC
Supplier Miltenyi Biotec
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About Vesicular Glutamate Transporter 1
The protein encoded by this gene is a vesicle-bound, sodium-dependent phosphate transporter that is specifically expressed in the neuron-rich regions of the brain. It is preferentially associated with the membranes of synaptic vesicles and functions in glutamate transport. The protein shares 82% identity with the differentiation-associated Na-dependent inorganic phosphate cotransporter and they appear to form a distinct class within the Na+/Pi cotransporter family. [provided by RefSeq, Jul 2008]
About APC
Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
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Validation References
PMID 15210307
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