UVRAG / Unconjugated /

Product Details
Description Rabbit anti-UVRAG IHC Antibody, Affinity Purified
Conjugate Unconjugated
Clone
Target Species Human, Mouse
Applications IHC
Supplier Bethyl Laboratories
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Host
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About UVRAG
This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer. [provided by RefSeq, Jul 2008]
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