Protein S / Unconjugated /

Product Details

Description	Polyclonal Rabbit Anti-Human Protein S, Unconjugated, Ig fraction, Precipitation, 1 mL. Protein S is a natural anticoagulant present in plasma. Patients deficient in protein S are subject to recurrent venous thrombotic disease. Protein S occurs in a functional, free form and in a non-functional complex with C4b-binding protein. This antibody reacts in gel precipitation techniques with both forms. These can be quantitated separately (1).
Conjugate	Unconjugated
Clone
Target Species	Human
Applications
Supplier	DAKO
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About Protein S
This gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Oct 2015]

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