CD61 / Unconjugated /

Product Details

Description	Monoclonal Mouse Anti-Human CD61, Platelet Glycoprotein IIIa, Clone Y2/51, Concentrated Antibody for Manual Use, Unconjugated, Culture supernatant, Immunohistochemistry, 1 mL. Platelet glycoprotein IIIa (GpIIIa) is identical to the Beta3-integrin subunit, which can associate with the AlphaV-chain (CD51) to form vitronectin receptor, or with the AlphaIIb-chain (CD41) to form the GpIIb/GpIIIa complex (CD41/CD61). The antibody detects platelets in smears of blood and bone marrow, as well as megakaryocytes in frozen sections and cell smears. The antibody is a useful aid for classification of megakaryoblastic leukemia.
Conjugate	Unconjugated
Clone
Target Species	Human
Applications
Supplier	DAKO
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About CD61
The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq, Jul 2008]

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