CACNA2D2 / Unconjugated / 3A4

Product Details
Description CACNA2D2 Antibody [3A4]
Conjugate Unconjugated
Clone 3A4
Target Species Human
Applications WB, IHC
Supplier ProSci
Catalog # Sign in to view product details, citations, and spectra
Size
Price
Antigen
Host
Isotype
About CACNA2D2
Calcium channels mediate the entry of calcium ions into the cell upon membrane polarization. This gene encodes the alpha-2/delta subunit of the voltage-dependent calcium channel complex. The complex consists of the main channel-forming subunit alpha-1, and auxiliary subunits alpha-2/delta, beta, and gamma. The auxiliary subunits function in the assembly and membrane localization of the complex, and modulate calcium currents and channel activation/inactivation kinetics. The subunit encoded by this gene undergoes post-translational cleavage to yield the extracellular alpha2 peptide and a membrane-anchored delta polypeptide. This subunit is a receptor for the antiepileptic drug, gabapentin. Mutations in this gene are associated with early infantile epileptic encephalopathy. Single nucleotide polymorphisms in this gene are correlated with increased sensitivity to opioid drugs. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014]
Experiment Design Tools
Conjugation Options

Pair this antibody with compatibility secondary antibodies, and conjugation kits and services:

Panel Builders

Looking to design a Microscopy or Flow Cytometry experiment?

Validation References
Additional
Sources
Reviews & Ratings
Looking for more options?

100 CACNA2D2 antibodies from over 13 suppliers available with over 16 conjugates.

 Compare