CD268 / ATTO 647N / HuBR9.1
Product Details
| Description | BAFF-R Antibody [HuBR9.1] (ATTO 647N) | |
|---|---|---|
| Conjugate | ATTO 647N | |
| Clone | HuBR9.1 | |
| Target Species | Human | |
| Applications | FC | |
| Supplier | ProSci | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About CD268
B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. [provided by RefSeq, Jul 2008]
B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. [provided by RefSeq, Jul 2008]
About ATTO 647N
ATTO 647N from ATTO-Tec Gmbh has an excitation peak at 644 nm and an emission peak at 669 nm.
ATTO 647N from ATTO-Tec Gmbh has an excitation peak at 644 nm and an emission peak at 669 nm.
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