ALOXE3 / Unconjugated /

Product Details
Description ALOXE3 Antibody
Conjugate Unconjugated
Clone
Target Species Human, Mouse
Applications WB
Supplier ProSci
Catalog # Sign in to view product details, citations, and spectra
Size
Price
Antigen
Host
Isotype
About ALOXE3
This gene is a member of the lipoxygenase family, which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha), which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis, implicating the function of this gene in the differentiation of human skin. This gene is part of a cluster of lipoxygenase genes on 17p13.1. Mutations in this gene result in nonbullous congenital ichthyosiform erythroderma (NCIE). Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
Experiment Design Tools
Conjugation Options

Pair this antibody with compatibility secondary antibodies, and conjugation kits and services:

Panel Builders

Looking to design a Microscopy or Flow Cytometry experiment?

Validation References
Additional
Sources
Reviews & Ratings
Looking for more options?

117 ALOXE3 antibodies from over 13 suppliers available with over 27 conjugates.

 Compare