Caveolin 1 / CoraLite 594 / 6C2B2
Product Details
Description | The Caveolin-1 antibody from Proteintech is a mouse monoclonal antibody to a fusion protein of human Caveolin-1. This antibody recognizes human,mouse,rat,pig antigen. The Caveolin-1 antibody has been validated for the following applications: IF, ELISA analysis. This antibody is coralite594-conjugated. | |
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Conjugate | CoraLite 594 | |
Clone | 6C2B2 | |
Target Species | Human, Mouse, Porcine, Rat | |
Applications | ELISA, IF | |
Supplier | Proteintech | |
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About Caveolin 1
The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq, Mar 2010]
The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq, Mar 2010]
About CoraLite 594
CoraLite 594 from Proteintech has an excitation peak at 594 nm and an emission peak at 615 nm. It is spectrally similar to Alexa Fluorâ„¢ 594, ATTO594 and DyLightâ„¢ 594 and can be useful in fluorescence microscopy.
CoraLite 594 from Proteintech has an excitation peak at 594 nm and an emission peak at 615 nm. It is spectrally similar to Alexa Fluorâ„¢ 594, ATTO594 and DyLightâ„¢ 594 and can be useful in fluorescence microscopy.
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