Catenin beta / CoraLite Plus 488 / 1B8A1
Product Details
Description | The beta-Catenin antibody from Proteintech is a mouse monoclonal antibody to a peptide of human beta-Catenin. This antibody recognizes human, mouse, rat, pig antigen. The beta-Catenin antibody has been validated for the following applications: IF, ELISA analysis. This antibody is coralite488-conjugated. | |
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Conjugate | CoraLite Plus 488 | |
Clone | 1B8A1 | |
Target Species | Human, Mouse, Porcine, Rat | |
Applications | ELISA, IF | |
Supplier | Proteintech | |
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About Catenin beta
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]
About CoraLite Plus 488
CoraLite Plus 488 from Proteintech has an excitation peak at 488 nm and an emission peak at 515 nm. It is spectrally similar to CF®488A and Alexa Fluor™ 488 and can be useful in fluorescence microscopy and flow cytometry.
CoraLite Plus 488 from Proteintech has an excitation peak at 488 nm and an emission peak at 515 nm. It is spectrally similar to CF®488A and Alexa Fluor™ 488 and can be useful in fluorescence microscopy and flow cytometry.
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