CD7 / VioBright FITC / CD7-6B7

Product Details

Description	Clone CD7-6B7 recognizes the human CD7 antigen, a single-pass type I membrane protein also known as leu-9 or GP40. CD7 appears early in T cell ontogeny and is expressed by most T cells in the periphery. It is also found on natural killer (NK) cells, hematopoietic progenitors, monocytes, acute lymphocytic leukemia, and some acute myeloid leukemia cells. Although the ligand is yet not identified, CD7 has been recognized as a costimulatory molecule. CD7 activates phosphatidylinositol 3-kinase which is involved in CD7-mediated regulation of integrin adhesiveness. Furthermore, it has been reported that the beta-galactoside-binding lectin galectin-1 binds CD7, leading to induction of apoptosis of thymocytes and T cells, with implications for certain autoimmune diseases and T cell lymphomas.
Conjugate	VioBright FITC
Clone	CD7-6B7
Target Species	Human
Applications	FC
Supplier	Miltenyi Biotec
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About CD7
This gene encodes a transmembrane protein which is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development. [provided by RefSeq, Jul 2008]

About VioBright FITC
Vio®Bright FITC has an excitation peak at 496 nm and an emission peak at 522 nm. It is recommended for use in flow cytometry and fluorescence microscopy.

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