NKp46 / Unconjugated / REA808

Product Details

Description	Clone REA808 recognizes the CD335 antigen, a type I membrane glycoprotein also known as NKp46. CD335 is a member of the natural cytotoxicity receptor (NCR) family which trigger cytotoxicity in natural killer (NK) cells and mediates cell activation. CD335 is directly involved in target cell recognition and lysis and is exclusively expressed on CD3–CD56+ NK cells, suggesting it to be a universal marker for NK cells. \| Additional information: Clone REA808 displays negligible binding to Fc receptors.
Conjugate	Unconjugated
Clone	REA808
Target Species	Human
Applications	Mass Cytometry
Supplier	Miltenyi Biotec
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About NKp46
Predicted to be involved in cellular defense response; regulation of natural killer cell mediated cytotoxicity; and signal transduction. Predicted to act upstream of or within defense response to virus and detection of virus. Predicted to be located in cell surface. Predicted to be part of SWI/SNF complex. Predicted to be active in plasma membrane. Biomarker of acquired immunodeficiency syndrome; anogenital venereal wart; hepatitis C; and lymphoproliferative syndrome. [provided by Alliance of Genome Resources, Apr 2022]

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