HLA-A2 / Biotin / REA517

Product Details

Description	Clone REA517 recognizes the class I human leukocyte antigen A2 (HLA-A2). Expressed on the surface of most nucleated cells, class I molecules are heterodimeric molecules and consist of a type I integral membrane alpha heavy chain and a soluble beta2 microglobulin protein. The extracellular region of the heavy chain further consists of three domains, one of which comprises the peptide binding groove. Antigens binding to class I molecules are 8–10 amino acids long and play an important role in recognition of virus infected and malignant cells by cytotoxic T lymphocytes (CTLs). In addition, class I molecules interact with NK cell receptors to modulate the activity of NK cells. \| Additional information: Clone REA517 displays negligible binding to Fc receptors.
Conjugate	Biotin
Clone	REA517
Target Species	Human
Applications	FC
Supplier	Miltenyi Biotec
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