FVS440UV / FVS440UV / Polyclonal
Product Details
| Description | BD Horizon Fixable Viability Stain 440UV (FVS440UV) is useful for discrimination of viable from non-viable mammalian cells in multicolor flow cytometric applications. This dye reacts with and covalently binds to cell-surface and intracellular amines. Permeable plasma cell membranes, such as those present in necrotic cells, allow for the intracellular diffusion of the dye and covalent binding to higher overall concentrations of amines than in non-permeable live cells. Therefore, necrotic cells present in a typical in vitro assay label with higher levels of dye increasing their fluorescence intensity 10-20 fold over that of viable cells. The labeled cells can be fixed with formaldehyde for downstream decontamination, freezing and/or permeabilization and subsequent intracellular staining while maintaining stable viability stain fluorescence. | |
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| Conjugate | FVS440UV | |
| Clone | Polyclonal | |
| Target Species | All Species | |
| Applications | FC | |
| Supplier | BD Biosciences | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About FVS440UV
FVS440UV (Fixable Viability Stain 440UV) is used as a flow cytometry viability dye to determine cellular viability in mammalian cells.
FVS440UV (Fixable Viability Stain 440UV) is used as a flow cytometry viability dye to determine cellular viability in mammalian cells.
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1 FVS440UV antibodies available with over 1 conjugates.
