CD14 / Brilliant Ultraviolet 496 / M5E2

Product Details
Description BUV496 Mouse Anti-Human CD14
Conjugate Brilliant Ultraviolet 496
Clone M5E2
Target Species Human
Applications FC
Supplier BD Biosciences
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About CD14
The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide, and to viruses. This gene has been identified as a target candidate in the treatment of SARS-CoV-2-infected patients to potentially lessen or inhibit a severe inflammatory response. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2020]
About Brilliant Ultraviolet 496
Brilliant™ UltraViolet 496 (BUV496) is a blue-emitting tandem fluorophore that combines BD Horizon® BUV395 and an acceptor dye. It can be excited by the 355 nm ultraViolet laser and collected using a 515/30 bandpass filter. BUV496 has an excitation peak at 348 nm and an emission peak at 496 nm BUV496 has a low/medium relative brightness, and is most commonly used for multicolor flow cytometry. This dye is part of the Brilliant™ UltraViolet dye family, developed and sold by BD Biosciences. This family of dyes uses BUV395 as the donor so that all dyes in the family can be excited by the 355 nm ultraViolet laser. Depending on the acceptor, the dyes in this family have different relative brightness ratings.
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