CD49d / Brilliant Ultraviolet 563 / MRalpha4-1

Product Details
Description BUV563 Mouse Anti-Rat CD49d
Conjugate Brilliant Ultraviolet 563
Clone MRalpha4-1
Target Species Rat
Applications FC
Supplier BD Biosciences
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About CD49d
The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
About Brilliant Ultraviolet 563
Brilliant™ UltraViolet 563 (BUV563) is a green-emitting tandem fluorophore that combines BD Horizon® BUV395 and an acceptor dye. It can be excited by the 355 nm ultraViolet laser and collected using a 585/15 bandpass filter. BUV563 has an excitation peak at 348 nm and an emission peak at 563 nm BUV563 has a medium relative brightness. This dye is part of the Brilliant™ UltraViolet dye family, developed and sold by BD Biosciences. This family of dyes uses BUV395 as the donor so that all dyes in the family can be excited by the 355 nm ultraViolet laser. Depending on the acceptor, the dyes in this family have different relative brightness ratings.
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