CD357 / DyLight 594 / RM0066-7C13

Product Details
Description Rat GITR/TNFRSF18 antibody reacts with Mouse [DyLight 594]
Conjugate DyLight 594
Clone RM0066-7C13
Target Species Mouse
Applications FC, IHC-P, IHC
Supplier Novus Biologicals
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About CD357
This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]
About DyLight 594
DyLight™ 594 has an excitation peak at 593 nm and an emission peak at 618 nm and is spectrally similar to Alexa Fluor™ 594 and Texas Red. DyLight™ 594 is most commonly used in flow cytometery and fluorescence microscopy applications.
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