AGR2 / DyLight 594 / 1000

Product Details
Description Mouse AG-2/AGR2 antibody [DyLight 594] detects Human, Mouse, Bovine, Canine, Equine, Primate
Conjugate DyLight 594
Clone 1000
Target Species Bovine, Canine, Equine, Human, Mouse, Primate
Applications IHC-P, WB, IHC
Supplier Novus Biologicals
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About AGR2
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression. [provided by RefSeq, Mar 2017]
About DyLight 594
DyLight™ 594 has an excitation peak at 593 nm and an emission peak at 618 nm and is spectrally similar to Alexa Fluor™ 594 and Texas Red. DyLight™ 594 is most commonly used in flow cytometery and fluorescence microscopy applications.
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500 AGR2 antibodies from over 23 suppliers available with over 41 conjugates.

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