About CD357
This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]

About Cy5
Cy5 is an important historical fluorophore from GE Healthcare. It has an excitation peak at 649 nm and an emission peak at 667 nm. Spectrally its similar to Alexa Fluor™ 647.