About PERK (pS713)
The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015]

About Alexa Fluor 680
Alexa Fluor™ 680 (AF680, Alexa 680) has an excitation peak at 679 nm and an emission peak at 702 nm, and is spectrally similar to Cy®5.5 (GE Healthcare), IR680® (Licor), iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 680 is commonly used for flow cytometry, fluorescence microscopy and super-resolution microscopy.