About NPR2
This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type. [provided by RefSeq, Jul 2008]

About Alexa Fluor 680
Alexa Fluor™ 680 (AF680, Alexa 680) has an excitation peak at 679 nm and an emission peak at 702 nm, and is spectrally similar to Cy®5.5 (GE Healthcare), IR680® (Licor), iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 680 is commonly used for flow cytometry, fluorescence microscopy and super-resolution microscopy.