Perforin / DyLight 680 / CB5.4

Product Details
Description Recognizes mouse perforin (region aa 402-534).
Conjugate DyLight 680
Clone CB5.4
Target Species Mouse
Applications FC, ICC, IF, IHC-P, WB, IHC-Fr, IHC
Supplier Novus Biologicals
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About Perforin
This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood. [provided by RefSeq, Aug 2017]
About DyLight 680
DyLight™ 680 has an excitation peak at 692 nm and an emission peak at 712 nm, and is spectrally similar to Alexa Fluor™ 680 and Cy5.5. DyLight™ 680 is most commonly used in flow cytometery and fluorescence microscopy applications.
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829 Perforin antibodies from over 39 suppliers available with over 64 conjugates.

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