CD200 R1 / DyLight 488 / OX-110

Product Details
Description NB100-63562 recognizes mouse CD200R, a cell surface glycoprotein (also known as OX2R), In mouse CD200R is expressed primarily by peripheral blood monocytes and neutrophils but also by other leucocytes including T-lymphocytes and mast cells (1). Studies suggest that CD200-CD200R interaction may be involved in the control of myeloid cellular function.
Conjugate DyLight 488
Clone OX-110
Target Species Mouse
Applications FC
Supplier Novus Biologicals
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About CD200 R1
This gene encodes a receptor for the OX-2 membrane glycoprotein. Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. Mouse studies of a related gene suggest that this interaction may control myeloid function in a tissue-specific manner. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
About DyLight 488
DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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430 CD200 R1 antibodies from over 22 suppliers available with over 41 conjugates.

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