Dnmt3b / APC /

Product Details
Description DNMT3B Antibody (aa581-859, APC)
Conjugate APC
Clone
Target Species Mouse
Applications WB
Supplier LifeSpan
Catalog # Sign in to view product details, citations, and spectra
Size
Price
Antigen
Host
Isotype
About Dnmt3b
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined. [provided by RefSeq, May 2011]
About APC
Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
Experiment Design Tools
Panel Builders

Looking to design a Microscopy or Flow Cytometry experiment?

Validation References
Additional
Sources
Reviews & Ratings
Looking for more options?

281 Dnmt3b antibodies from over 23 suppliers available with over 18 conjugates.

 Compare