Complement Factor MASP3 Catalytic Domain / Biotin /

Product Details
Description MASP1 / MASP Antibody (aa20-447, Biotin)
Conjugate Biotin
Clone
Target Species Human, Mouse
Applications WB
Supplier LifeSpan
Catalog # Sign in to view product details, citations, and spectra
Size
Price
Antigen
Host
Isotype
About Complement Factor MASP3 Catalytic Domain
This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]
Experiment Design Tools
Panel Builders

Looking to design a Microscopy or Flow Cytometry experiment?

Validation References
Additional
Sources
Reviews & Ratings
Looking for more options?

192 Complement Factor MASP3 Catalytic Domain antibodies from over 11 suppliers available with over 28 conjugates.

 Compare