Actin Alpha 1 (Skeletal Muscle) / DyLight 350 / 22D3

Product Details
Description Clone 22D3 is an antibody highly specific for a- cardiac actin, and does not cross react with other actin isoforms.
Conjugate DyLight 350
Clone 22D3
Target Species Bovine, Goat, Human, Mammal, Mouse, Porcine, Rabbit, Rat, Xenopus, Zebrafish
Applications ELISA, ICC, IF, IHC-P, WB, IHC
Supplier Novus Biologicals
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About Actin Alpha 1 (Skeletal Muscle)
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause a variety of myopathies, including nemaline myopathy, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects with manifestations such as hypotonia. [provided by RefSeq, Sep 2019]
About DyLight 350
DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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