Desmoglein-3 / DyLight 405 / 5G11

Product Details
Description This antibody reacts with Desmoglein 3. Does not cross-react with Desmoglein 1 or Desmoglein 2.
Conjugate DyLight 405
Clone 5G11
Target Species Human
Applications FC, ICC, IF, IHC-P, WB, IHC
Supplier Novus Biologicals
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About Desmoglein-3
This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris. [provided by RefSeq, Jan 2016]
About DyLight 405
DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications.
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