TrkA / Biotin /

Product Details
Description NTRK1 / TrkA Antibody (Biotin)
Conjugate Biotin
Clone
Target Species Human, Mouse, Rat
Applications ICC, WB, IP, IHC
Supplier LifeSpan
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Isotype
About TrkA
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008]
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