ARRB1 / Biotin /

Product Details
Description ARRB1 / Beta Arrestin 1 Antibody (Biotin)
Conjugate Biotin
Clone
Target Species Human
Applications IF, WB
Supplier LifeSpan
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About ARRB1
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011]
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260 ARRB1 antibodies from over 13 suppliers available with over 18 conjugates.

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