Tmp21/p23 / HRP /
Product Details
| Description | TMED10 / TMP21 Antibody (aa143-192, HRP) | |
|---|---|---|
| Conjugate | HRP | |
| Clone | ||
| Target Species | Bovine, Canine, Chicken, Chimpanzee, Equine, Gibbon, Guinea Pig, Hamster, Human, Monkey, Mouse, Porcine, Rabbit, Rat, Xenopus, Zebrafish | |
| Applications | WB | |
| Supplier | LifeSpan | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About Tmp21/p23
This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq, Jul 2008]
This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq, Jul 2008]
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