PITX2 / HRP /

Product Details
Description PITX2 / RGS Antibody (N-Terminus, HRP)
Conjugate HRP
Clone
Target Species Chimpanzee, Human, Monkey
Applications WB
Supplier LifeSpan
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About PITX2
This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
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196 PITX2 antibodies from over 14 suppliers available with over 16 conjugates.

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