BCL2L2 / Unconjugated /

Product Details
Description BCL2L2 / Bcl-w Antibody (100-180 aa, C-terminal)
Conjugate Unconjugated
Clone
Target Species Human, Mouse, Rat
Applications ELISA, IF, WB, IHC
Supplier LifeSpan
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About BCL2L2
This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene. [provided by RefSeq, Dec 2010]
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