Ubinuclein 1 / Unconjugated / UBN1G12
Product Details
Description | UBN1 / Ubinuclein 1 Antibody (clone UBN1G12) | |
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Conjugate | Unconjugated | |
Clone | UBN1G12 | |
Target Species | Human | |
Applications | WB, Dot Blot | |
Supplier | LifeSpan | |
Catalog # | Sign in to view product details, citations, and spectra | |
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About Ubinuclein 1
Cellular senescence is a hallmark of tumor suppression and tissue aging. Senescent cells contain domains of heterochromatin, called senescence-associated heterochromatin foci (SAHF), that repress proliferation-promoting genes. The protein encoded by this gene binds to proliferation-promoting genes and is required for SAHF formation, enhancing methylation of histone H3. [provided by RefSeq, Oct 2016]
Cellular senescence is a hallmark of tumor suppression and tissue aging. Senescent cells contain domains of heterochromatin, called senescence-associated heterochromatin foci (SAHF), that repress proliferation-promoting genes. The protein encoded by this gene binds to proliferation-promoting genes and is required for SAHF formation, enhancing methylation of histone H3. [provided by RefSeq, Oct 2016]
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