CD62L / V450 / DREG-56

Product Details
Description V450 Mouse Anti-Human CD62L
Conjugate V450
Clone DREG-56
Target Species Human
Applications FC
Supplier BD Biosciences
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About CD62L
This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]
About V450
V450 (Horizon V450) from BD Biosciences has an excitation peak at 406 nm and an emission peak at 450 nm. It is spectrally similar to eFluor™ 450 (ThermoFisher Scientific), Vio®Blue® (Miltenyi Biotec), Alexa Fluor™ 405 (ThermoFisher Scientific), Cascade Blue® (ThermoFisher Scientific), Pacific Blue (ThermoFisher Scientific), and ATTO 425 (ATTO-Tec)
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