About CD27
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]

About APC-H7
APC-H7 from BD Biosciences has an excitation peak at 651 nm and an emission peak at 785 nm. It's useful in flow cytometry and is spectrally similar to APC-Alexa 750, APC-CF®770, APC-Cy7, APC-Fire™ 750, APC-Vio®770, APC-eFluor™ 780 and Seta-APC-780.