ERLIN1 / HRP /
Product Details
Description | ERLIN1 / SPFH1 Antibody (aa244-273, Azide-free, HRP) | |
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Conjugate | HRP | |
Clone | ||
Target Species | Human | |
Applications | ELISA, WB, IHC | |
Supplier | LifeSpan | |
Catalog # | Sign in to view product details, citations, and spectra | |
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Price | ||
Antigen | ||
Host | ||
Isotype |
About ERLIN1
The protein encoded by this gene is part of a protein complex that mediates degradation of inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum. The encoded protein also binds cholesterol and regulates the SREBP signaling pathway, which promotes cellular cholesterol homeostasis. Defects in this gene have been associated with spastic paraplegia 62. [provided by RefSeq, Dec 2016]
The protein encoded by this gene is part of a protein complex that mediates degradation of inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum. The encoded protein also binds cholesterol and regulates the SREBP signaling pathway, which promotes cellular cholesterol homeostasis. Defects in this gene have been associated with spastic paraplegia 62. [provided by RefSeq, Dec 2016]
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