ERLIN2 / Alk Phosphatase /
Product Details
| Description | SPFH2 / ERLIN2 Antibody (aa307-333, AP) | |
|---|---|---|
| Conjugate | Alk Phosphatase | |
| Clone | ||
| Target Species | Human | |
| Applications | ELISA, WB | |
| Supplier | LifeSpan | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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| Antigen | ||
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About ERLIN2
This gene encodes a member of the SPFH domain-containing family of lipid raft-associated proteins. The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1,4,5-trisphosphate (IP3) signaling by mediating ER-associated degradation of activated IP3 receptors. Mutations in this gene are a cause of spastic paraplegia-18 (SPG18). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]
This gene encodes a member of the SPFH domain-containing family of lipid raft-associated proteins. The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1,4,5-trisphosphate (IP3) signaling by mediating ER-associated degradation of activated IP3 receptors. Mutations in this gene are a cause of spastic paraplegia-18 (SPG18). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]
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