ADRA2C / ATTO 633 / S330A-80
Product Details
Description | ADRA2C Antibody (aa442-462, clone S330A-80, Atto 633) | |
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Conjugate | ATTO 633 | |
Clone | S330A-80 | |
Target Species | Human, Mouse | |
Applications | ICC, WB | |
Supplier | LifeSpan | |
Catalog # | Sign in to view product details, citations, and spectra | |
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About ADRA2C
Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008]
Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008]
About ATTO 633
ATTO 633 from ATTO-Tec Gmbh has an excitation peak at 629 nm and an emission peak at 657 nm.
ATTO 633 from ATTO-Tec Gmbh has an excitation peak at 629 nm and an emission peak at 657 nm.
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