NMDAR NR2A / ATTO 390 / S327-95
Product Details
Description | GRIN2A / NMDAR2A / NR2A Antibody (aa75-325, clone S327-95, Atto 390) | |
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Conjugate | ATTO 390 | |
Clone | S327-95 | |
Target Species | Human, Mouse, Rat | |
Applications | ICC, WB, IHC | |
Supplier | LifeSpan | |
Catalog # | Sign in to view product details, citations, and spectra | |
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About NMDAR NR2A
This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
About ATTO 390
ATTO 390 from ATTO-Tec Gmbh has an excitation peak at 390 nm and an emission peak at 448 nm.
ATTO 390 from ATTO-Tec Gmbh has an excitation peak at 390 nm and an emission peak at 448 nm.
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