ANAPC2 / Unconjugated / 30

Product Details
Description ANAPC2 / APC2 Antibody (clone 3E1)
Conjugate Unconjugated
Clone 30
Target Species Human
Applications FC, IF, WB
Supplier LifeSpan
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About ANAPC2
A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation. [provided by RefSeq, Jul 2008]
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