Endothelin B Receptor / Sepharose /
Product Details
| Description | EDNRB / Endothelin B Receptor Antibody (Internal, Sepharose) | |
|---|---|---|
| Conjugate | Sepharose | |
| Clone | ||
| Target Species | Human | |
| Applications | WB, IP, IHC | |
| Supplier | LifeSpan | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About Endothelin B Receptor
The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016]
The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016]
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