SURF1 / Unconjugated /

Product Details
Description SURF1 Antibody (aa171-220) IHC-plus‚Ñ¢
Conjugate Unconjugated
Clone
Target Species Human, Mouse, Rat
Applications ELISA, IHC-P, WB, IHC
Supplier LifeSpan
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About SURF1
This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency. [provided by RefSeq, Jul 2008]
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